If necessary, you can use cooked, defrosted shrimp instead of raw shrimp. I've even used frozen, cooked shrimp and added it directly to the orzo when the shrimp is still frozen. Both work okay, but tend to bring down the temperature of the whole dish so neither the orzo or the shrimp are hot when you're ready to eat.
White wine is optional, but does add more flavor to the orzo. If you don't have white wine, just skip it and move on to the next step in the recipe.
This pasta can also be served as a cold shrimp and orzo pasta salad. Let the orzo and shrimp cool completely. Add mayonnaise and more lemon juice, plus salt and pepper to taste.
This recipe was tested in a 6-quart Instant Pot.